VANCOUVER, BC, May 2, 2022 /PRNewswire/ -- The global DNA methylation size reached USD 2.08 billion in 2021 and is expected to register a significantly steady revenue CAGR during the forecast period, according to latest analysis by Emergen Research. Rising usage of DNA methylation in DNA sequencing analyses and increasing adoption of the technique in agrigenomic investigations are major factors expected to drive market revenue growth during the forecast period.
Drivers:
Increasing adoption of DNA methylation in various sequencing methods such as pyro-sequencing, Illumina sequencing, Ion-Torrent, and Oxford Nanopore sequencing is driving demand. In addition, DNA methylation is widely used as an epigenetic biomarker in oncology research laboratories across the globe. DNA methylation technology is increasingly being used in academic and cancer research, driven by increasing prevalence of different cancers globally. In addition, alternative diagnostic methods are being adopted for early detection of genetic disorders. These are some of the key factors expected to drive market revenue growth to a major extent going ahead.
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Restraints:
Expertise is lacking in the field of biotechnology to enable conducting of DNA methylation experiments. DNA methylation shows promising results in the field of biotechnology field, but availability of skilled lab technicians is relatively low. Low adoption of DNA methylation as a commercial diagnostic test are a potential restraining factor for DNA methylation market growth. Although it provides promising results in the field of basic and applied genomics research, commercialization of the technique as a medical diagnostic test has seen not been possible.
Growth Projections:
The global DNA methylation market is expected to register a CAGR of 15.9% over the forecast period, and revenue growth is projected to increase from USD 2.08 billion in 2021 to USD 7.79 billion in 2030. Increasing usage of DNA methylation in oncology research is a key factor driving market growth.
COVID-19 Impact Analysis:
The COVID-19 pandemic resulted in lockdowns and restrictions in terms of movement, which also resulted in stalled research and testing at laboratories and research centers globally. However, reopening of academic and research institutions has led to increased usage of DNA methylation. In addition, availability of a wide range of DNA methylation test kits through e-Commerce channels has further opened up opportunities for players in the market. This has also led to increased adoption of DNA methylation in academic institutions.
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Current Trends and Innovations:
Demand for DNA methylation as epigenetic biomarkers in clinical laboratories for detection of genomic disorders has been increasing owing to increasing number of research activities being conducted in the recent past, which is expected to drive market revenue growth. DNA methylation is widely used in DNA sequencing, as well as genomic analyses studies. This is expected to boost market revenue growth significantly during the forecast period.
Geographical Outlook:
North America is expected to register a rapid revenue growth rate during the forecast period. This can be attributed to increasing usage of DNA methylation as an epigenetic biomarker and increased usage in the research sector.
Strategic Initiatives:
Some major companies included in the market report are New England Biolabs, Merck KGaA, Pacific Biosciences, Inc., Thermo-Fisher Scientific, Inc., Illumina, Inc., Bio-Rad Laboratories, Inc., Sysmex Corporation, Abcam plc., F. Hoffmann-La Roche Ltd., and Diagenode Diagnostics S.A.
- In February 2022, New England Biolabs announced a partnership with EpiCypher, Inc., in order to co-develop library prep kits specifically optimized for providing the best performance with CUTANA CUT&RUN epigenomic assays of the latter company. CUTANA CUT&RUN epigenomic assay of the EpiCypher, Inc. has been steadily replacing chromatin immunoprecipitation sequencing to be the leading technology in chromatin mapping. The current product is expected to address the concerns regarding complicated assay development, high reaction costs, and low-yield experiment adaptation.
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Emergen Research has segmented the global DNA methylation market on the basis of technology, application, end-use, and region:
- Technology Outlook (Revenue, USD Billion, 2019–2030)
- Bisulfite DNA Modification
- Methylated DNA Immunoprecipitation
- High-Resolution Melt Analysis
- Others
- Application Outlook (Revenue, USD Billion, 2019–2030)
- DNA Sequencing
- Oncology Research
- Microarray
- Immunological Assay
- Others
- End-Use Outlook (Revenue, USD Billion, 2019–2030)
- Biotechnology Industry
- Pharmaceutical Industry
- Academic Institutions
- Research Laboratories
- Others
- Product Outlook (Revenue, USD Billion, 2019–2030)
- Enzymes
- Reagents
- Kits
- Instruments and Consumables
- Others
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- Regional Outlook (Revenue, USD Billion, 2019–2030)
- North America
- a. U.S.
- b. Canada
- c. Mexico
- o Europe
- a. Germany
- b. France
- c. U.K.
- d. Italy
- e. Spain
- f. Benelux
- g. Rest of Europe
- Asia Pacific
- a. China
- b. India
- c. Japan
- d. South Korea
- e. Rest of APAC
- Latin America
- a. Brazil
- b. Rest of LATAM
- Middle East & Africa
- a. Saudi Arabia
- b. UAE
- c. South Africa
- d. Turkey
- e. Rest of MEA
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