Type 1 Diabetes: Reliable Insulin Delivery That Suits Patient’s Lifestyles - touchENDOCRINOLOGY

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11 May, 2017, 11:00 GMT

LONDON, May 11, 2017 /PRNewswire/ --

Stephen C Bain, European Endocrinology, 2017;13(1):13-6: https://doi.org/10.17925/EE.2017.13.01.13

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Published recently in European Endocrinology, the peer-reviewed journal from touchENDOCRINOLOGY, Stephen C Bain presents a review of the Cellnovo insulin delivery system. Autoimmune destruction of pancreatic beta-cells results in absolute insulin deficiency, type 1 diabetes mellitus (T1DM). Insulin therapy is required for people with T1DM to achieve an optimal glycated haemoglobin (HbA1c or A1c) along with controlled dayto- day blood glucose (BG) levels. While a variety of insulin delivery systems are available, factors such as the complexity of dosage calculation based on activity, diet and BG, the effectiveness of insulin delivery, ease of product use and 'human' issues, may affect concordance with treatment (see Table 1).[1],[2] Using an insulin delivery system which suits the patient's lifestyle and addresses issues of delivery reliability may improve concordance and ameliorate BG variability. Continuous subcutaneous insulin infusion (CSII) therapy has been shown to:
• ensure accurate insulin delivery leading to improved A1c;[3]
• eliminate the unpredicatable effects of intermediate or long-acting insulin;[3]
• reduce severe low BG episodes; and[3]
• facilitate easier delivery of bolus insulin.[3]

The full peer-reviewed, open-access article is available here:

https://doi.org/10.17925/EE.2017.13.01.13

Disclosure: Stephen C Bain is a member of the Cellnovo Medical Advisory Board. This article is a short opinion piece and has not been submitted to external peer reviewers, but the questions were reviewed by the Editorial Board before publication.

Note to the Editor

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References:

[1] Skovlund SE, Peyrot M, The Diabetes Attitudes, Wishes and Needs (DAWN) Program: A new approach to improving outcomes in diabetes care, Diabetes Spectrum, 2005;18(3):136-42. 
[2] Nicolucci A, Kovacs Burns K, Holt RIG, et al., Diabetes Attitudes, Wishes and Needs second study (DAWN 2): Cross-national benchmarking of diabetes-related psychosocial outcomes for people with diabetes, Diabetic Medicine, 2013;30(7):767-77.
[3] American Diabetes Association, Advantages of Using an Insulin Pump, 2015. Available at: http://www.diabetes.org/living-with-diabetes/treatment-and-care/medication/insulin/advantages-of-using-an-insulin-pump.html  (accessed 3 October 2016).